Principles of Neural Science, Fifth Edition ) Author: Eric Kandel James Schwartz Thomas Jessell Steven Siegelbaum A.J. Hudspeth Eric R. Kandel James H. Schwartz Thomas M. Jessell Steven A. Siegelbaum A. J. Hudspeth | Language: English | ISBN:
B009LHFYNG | Format: PDF
Principles of Neural Science, Fifth Edition ) Description
Now updated: the definitive neuroscience resource—from Eric R. Kandel, MD (winner of the Nobel Prize in 2000); James H. Schwartz, MD, PhD; Thomas M. Jessell, PhD; Steven A. Siegelbaum, PhD; and A. J. Hudspeth, PhD
900 full-color illustrations
Deciphering the link between the human brain and behavior has always been one of the most intriguing—and often challenging—aspects of scientific endeavor. The sequencing of the human genome, and advances in molecular biology, have illuminated the pathogenesis of many neurological diseases and have propelled our knowledge of how the brain controls behavior.
To grasp the wider implications of these developments and gain a fundamental understanding of this dynamic, fast-moving field, Principles of Neuroscience stands alone as the most authoritative and indispensible resource of its kind.
In this classic text, prominent researchers in the field expertly survey the entire spectrum of neural science, giving an up-to-date, unparalleled view of the discipline for anyone who studies brain and mind. Here, in one remarkable volume, is the current state of neural science knowledge—ranging from molecules and cells, to anatomic structures and systems, to the senses and cognitive functions—all supported by more than 900 precise, full-color illustrations. In addition to clarifying complex topics, the book also benefits from a cohesive organization, beginning with an insightful overview of the interrelationships between the brain, nervous system, genes, and behavior. Principles of Neural Science then proceeds with an in-depth examination of the molecular and cellular biology of nerve cells, synaptic transmission, and the neural basis of cognition. The remaining sections illuminate how cells, molecules, and systems give us sight, hearing, touch, movement, thought, learning, memories, and emotions.
The new fifth edition of Principles of Neural Science is thoroughly updated to reflect the tremendous amount of research, and the very latest clinical perspectives, that have significantly transformed the field within the last decade.
Ultimately, Principles of Neural Science affirms that all behavior is an expression of neural activity, and that the future of clinical neurology and psychiatry hinges on the progress of neural science. Far exceeding the scope and scholarship of similar texts, this unmatched guide offers a commanding, scientifically rigorous perspective on the molecular mechanisms of neural function and disease—one that you’ll continually rely on to advance your comprehension of brain, mind, and behavior.
FEATURES
- The cornerstone reference in the field of neuroscience that explains how the nerves, brain, and mind function
- Clear emphasis on how behavior can be examined through the electrical activity of both individual neurons and systems of nerve cells
- Current focus on molecular biology as a tool for probing the pathogenesis of many neurological diseases, including muscular dystrophy, Huntington disease, and certain forms of Alzheimer’s disease
- More than 900 engaging full-color illustrations—including line drawings, radiographs, micrographs, and medical photographs clarify often-complex neuroscience concepts
- Outstanding section on the development and emergence of behavior, including important coverage of brain damage repair, the sexual differentiation of the nervous system, and the aging brain
- NEW! More detailed discussions of cognitive and behavioral functions, and an expanded review of cognitive processes
- NEW! A focus on the increasing importance of computational neural science, which enhances our ability to record the brain’s electrical activity and study cognitive processes more directly
- NEW! Chapter-opening Key Concepts provide a convenient, study-enhancing introduction to the material covered in each chapter
- Selected Readings and full reference citations at the close of each chapter facilitate further study and research
- Helpful appendices highlight basic circuit theory; the neurological examination of the patient; circulation of the brain; the blood-brain barrier, choroid plexus, and cerebrospinal fluid; neural networks; and theoretical approaches to neuroscience
- File Size: 316945 KB
- Print Length: 1760 pages
- Simultaneous Device Usage: Up to 4 simultaneous devices, per publisher limits
- Publisher: McGraw-Hill Professional; 5th edition (September 27, 2012)
- Sold by: Amazon Digital Services, Inc.
- Language: English
- ASIN: B009LHFYNG
- Text-to-Speech: Enabled
X-Ray:
- Lending: Not Enabled
- Amazon Best Sellers Rank: #73,837 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
- #50
in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Internal Medicine > Neurology > Neuroscience
- #50
in Kindle Store > Kindle eBooks > Nonfiction > Professional & Technical > Medical eBooks > Internal Medicine > Neurology > Neuroscience
I purchased the 4th edition of Principles of Neural Science back in 2001, when I was studying at McGill in cognitive science and neuroscience. This was the most useful introduction on the subject matter of neuroscience, and its amazing breadth and depth was sufficient to cover all the basics and find references for further readings on specific topics.
I used it extensively when I started my PhD in cognitive science at Carleton University and had a challenging, full-year course in behavioral neuroscience. The fourth edition has aged well as an introduction, but the neuroscience community was longing for an update in a field which is less forgiving about years-old sources. It is sad that it took 12 years (!) for an update, but what an update it is!
The 5th edition clocks at 350 additional pages approximately, and while the original material has been preserved where it is required, it *has been updated*. Sections on cognitive processes and behavioral features have been added, more details on aging and neuropathologies/lesions, and of course, the artwork is wonderful. It is slightly more pedagogically-oriented, which was not even a shortcoming in the previous edition. Awesome updates on the reference material to cover the work between 2000 and 2008-ish (I know, it's not up to 2012, but that's how editing and publishing works, viz., slowly).
The icing on the cake is the new computational neuroscience stuff, which is to me invaluable, considering that I study cognitive science in general, and computational cognitive modeling in particular. Add appendices on the theory of neural wiring/engineering and computational modelling, and this is a good A+.
I might be biased, since I wanted this book to be awesome, but hey, they did it again.
After its release was pushed back many times, the 5th edition finally came out within the past year, and I have been reading it on my laptop's Kindle app throughout my first year of core PhD courses and in preparing for my qualifying exam. I had read some of the 4th edition during undergrad, as well.
In general my feelings towards the book are warm, and I do expect that if you read the textbook, dear reader of this review, you will learn a lot from it.
Positives
1) Does a good job of not trying to be Alberts' *Molecular Biology of the Cell*. The sections on cell biology, the central dogma, and non-neuroscience-related signaling pathways are refreshingly bare-boned. Seek resources elsewhere if you want to go ham on transcription, translation, and the MAPKKK-MAPKK-MAPK cascade.
2) Perception, sensation, and movement were not the reasons that I first became interested in neuroscience, and, generalizing from my one example as is de rigueur in book reviews, I think that is true of most students. And while this might be just Stockholm syndrome, I'm actually quite happy that there is so much detail and care put into these sections which make up around 1/3rd of the text. These fields are way more tractable to study than the sexy emotion, learning, and personal identity, yet the most of the principles that have been discovered there are likely to generalize.
As an example of this, consider the work of Charles Sherrington, who among other accomplishments won the 1932 Nobel for explaining spinal reflexes as a balance of excitation and inhibition.
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